alzheimer's disease

Speech based biomarkers for monitoring progressive changes in Alzheimer’s disease

A speech based composite which tracks change in AD over time was recently developed and piloted through a collaboration between Winterlight Labs and Genentech.

Speech is a rich source of clinical information when assessing and monitoring Alzheimer’s Disease. Natural language processing technologies, like those developed by Winterlight Labs, can objectively quantify speech and enable its use as a novel endpoint in drug development.

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The next generation of treatments for Alzheimer’s Disease in clinical trials

The latest advances in the treatment of Alzheimer’s disease and how Cambridge Cognition are designing and implementing empirically validated and clinically-relevant cognitive tasks to help develop the next generation of Alzheimer’s disease treatments. 

There are presently over 140 drugs being explored as possible treatments for Alzheimer’s Disease (AD) in clinical trials. Of these, nearly 80% are intended to slow the progression of AD. Historically, cholinesterase inhibitor drugs such as galantamine, rivastigmine and donepezil have been approved for treatment of AD. These drugs have been shown to mitigate symptoms of AD, such as memory loss, however they are unable to treat the underlying neurobiological cause of the condition. As such, these drugs do not slow AD progression and are not considered a long-term solution in the battle to end the most common form of neurodegenerative disease.

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Using CANTAB to develop AI-based tools for the early detection of dementia

Insights Back to resource centre 21 September 2022 Using CANTAB to develop AI-based tools for the early detection of dementia To mark World Alzheimer’s Day, we hear from Christoffer Hatlestad-Hall and his team at Oslo University Hospital, who explain how CANTABTM is an instrumental part of their study using AI and machine learning to identify the earliest signs of Alzheimer’s

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Using CANTAB to identify undiagnosed dementia cases using a web-based pre-screening tool in the MOPEAD project

Insights Back to resource centre 22 November 2021 Using CANTAB to identify undiagnosed dementia cases using a web-based pre-screening tool in the MOPEAD project We recently caught up with Dr. Mercè Boada, the project coordinator of MOPEAD, and Medical Director of Ace Alzheimer Center Barcelona to discuss her recent publication supporting the use of CANTAB for the early detection of

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Shows the nutrients in the brain

Using CANTAB to examine the potential synergistic effects of a combination of omega-3 fatty acids, carotenoids and vitamin E on the cognitive health and function of patients with MCI.

Insights Back to resource centre 16 November 2020 Using CANTAB to examine the potential synergistic effects of a combination of omega-3 fatty acids, carotenoids and vitamin E on the cognitive health and function of patients with MCI. Dr Rebecca Power, Postdoctoral Researcher at the Nutrition Research Centre Ireland, shared the role that CANTAB played in her latest publication: Targeted Nutritional

Using CANTAB to examine the potential synergistic effects of a combination of omega-3 fatty acids, carotenoids and vitamin E on the cognitive health and function of patients with MCI. Read More »

CANTAB tests predict change in global functioning in patients with amnestic mild cognitive impairments

CANTAB tests predict functional decline in patients with amnestic mild cognitive impairment

Insights Back to resource centre 25 October 2018 CANTAB tests predict functional decline in patients with amnestic mild cognitive impairment We presented a novel, predictive model of functional decline at CTAD 2018. The model suggests that CANTAB PAL and SWM provide essential screening information when recruiting patients with amnestic mild cognitive impairment into Alzheimer’s disease clinical trials. BackgroundDetecting the progression

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