cantab

Speech based biomarkers for monitoring progressive changes in Alzheimer’s disease

A speech based composite which tracks change in AD over time was recently developed and piloted through a collaboration between Winterlight Labs and Genentech.

Speech is a rich source of clinical information when assessing and monitoring Alzheimer’s Disease. Natural language processing technologies, like those developed by Winterlight Labs, can objectively quantify speech and enable its use as a novel endpoint in drug development.

The next generation of treatments for Alzheimer’s Disease in clinical trials

The latest advances in the treatment of Alzheimer’s disease and how Cambridge Cognition are designing and implementing empirically validated and clinically-relevant cognitive tasks to help develop the next generation of Alzheimer’s disease treatments. 

There are presently over 140 drugs being explored as possible treatments for Alzheimer’s Disease (AD) in clinical trials. Of these, nearly 80% are intended to slow the progression of AD. Historically, cholinesterase inhibitor drugs such as galantamine, rivastigmine and donepezil have been approved for treatment of AD. These drugs have been shown to mitigate symptoms of AD, such as memory loss, however they are unable to treat the underlying neurobiological cause of the condition. As such, these drugs do not slow AD progression and are not considered a long-term solution in the battle to end the most common form of neurodegenerative disease.

Using a multidisciplinary approach to characterise the neurobiology of addiction

Insights Back to resource centre 6 October 2022 Understanding the effect of ashwagandha root extract on stress, sleep and cognition We caught up with Shefali Thanawala from Nutriventia Ltd who told us how CANTAB™ helped them to investigate the effects of Ashwagandha root extract on memory and focus in healthy, stressed adults. About Nutriventia, Ltd.Nutriventia Limited is the dietary supplements

Team members from University of Sinagpore

Measuring cognition in areas outside of the Central Nervous System

Insights Back to resource centre 24 April 2023 Measuring cognition in areas outside of the Central Nervous System CANTAB® cognitive assessments are often used to measure cognition in disorders of the Central Nervous System, but did you know that they are also used in research that don’t involve the CNS? Here, two research teams explain how CANTAB is supporting their

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Using CANTAB to understand more about depth of anaesthesia and post-operative cognitive dysfunction

Insights Back to resource centre 21 March 2023 Using CANTAB to understand more about depth of anaesthesia and post-operative cognitive dysfunction We caught up with Anders Aasheim from Oslo University Hospital who told us more about his team’s research in understanding the effect of anaesthesia on cognitive function. My name is Anders Aasheim, and I am a nurse anaesthetist and

My career story: Naomi McPartlan, Clinical Project Coordinator

Insights Back to resource centre 15 March 2023 My career story: Naomi McPartlan, Clinical Project Coordinator We chatted to Naomi about her role, her career to date and what advice she has for anyone thinking of a career in clinical trials and health technology.When did you join Cambridge Cognition and what is your role?I started at the beginning of July 2022 as

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How CANTAB can help to understand cognition in eating disorders

Insights Back to resource centre 2 March 2023 How CANTAB can help to understand cognition in eating disorders During Eating Disorder Awareness Week (27th February – 5th March), Hannah Hickinbotham and Eleanor Rist reflect on the evidence around how cognition is affected in eating disorders, and how CANTAB® can be used for research in this area. Around 1.25 million people

Age-Related Cognitive Changes in the Cambridge Neuropsychological Test Automated Battery (CANTAB) Normative Sample

Insights Back to resource centre 6 October 2022 Understanding the effect of ashwagandha root extract on stress, sleep and cognition We caught up with Shefali Thanawala from Nutriventia Ltd who told us how CANTAB™ helped them to investigate the effects of Ashwagandha root extract on memory and focus in healthy, stressed adults. About Nutriventia, Ltd.Nutriventia Limited is the dietary supplements

The role of cognitive functions in the diagnosis of bipolar disorder: A machine learning model

Insights Back to resource centre 1 February 2023 The role of cognitive functions in the diagnosis of bipolar disorder: A machine learning model We caught up with Ercan Altınöz, Associate Professor of Psychiatry at Eskişehir Osmangazi University School of Medicine in Eskişehir, Turkey, who told us how combining CANTAB® tasks with machine learning may help to improve diagnosis of bipolar

How CANTAB can be used to overcome challenges in assessing cognition in people with intellectual disabilities

Insights Back to resource centre 17 January 2023 How CANTAB can be used to overcome challenges in assessing cognition in people with intellectual disabilities Operational scientist Eleanor Rist explores how CANTAB™ assessments can be beneficial for studies involving people with intellectual disabilities. Intellectual disabilities, often referred to as learning disabilities in the UK, are generally defined as having an IQ

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