cognitive assessment

Speech based biomarkers for monitoring progressive changes in Alzheimer’s disease

A speech based composite which tracks change in AD over time was recently developed and piloted through a collaboration between Winterlight Labs and Genentech.

Speech is a rich source of clinical information when assessing and monitoring Alzheimer’s Disease. Natural language processing technologies, like those developed by Winterlight Labs, can objectively quantify speech and enable its use as a novel endpoint in drug development.

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The next generation of treatments for Alzheimer’s Disease in clinical trials

The latest advances in the treatment of Alzheimer’s disease and how Cambridge Cognition are designing and implementing empirically validated and clinically-relevant cognitive tasks to help develop the next generation of Alzheimer’s disease treatments. 

There are presently over 140 drugs being explored as possible treatments for Alzheimer’s Disease (AD) in clinical trials. Of these, nearly 80% are intended to slow the progression of AD. Historically, cholinesterase inhibitor drugs such as galantamine, rivastigmine and donepezil have been approved for treatment of AD. These drugs have been shown to mitigate symptoms of AD, such as memory loss, however they are unable to treat the underlying neurobiological cause of the condition. As such, these drugs do not slow AD progression and are not considered a long-term solution in the battle to end the most common form of neurodegenerative disease.

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Remote cognitive testing: what are the scientific and operational considerations?

Insights Back to resource centre 11 June 2020 Remote cognitive testing: what are the scientific and operational considerations? Remote testing solutions for clinical trials and academic research are increasingly being adopted resulting in time and cost savings for clinical research studies and reduced participation burden for study patients. However, not every study is suitable for this medium. In this article

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7 tests for assessing cognition in early Alzheimer’s disease

Insights Back to resource centre 27 April 2018 7 tests for assessing cognition in early Alzheimer’s disease With rising life-expectancy, the number of cases of dementia and related disorders is increasing. In attempts to tackle the pandemic, treatment trials are moving earlier in the disease process. CANTAB offers a battery of tests specially targeted at assessing cognition in early Alzheimer’s

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Pen-and-paper vs. computerised testing: which method do older adults prefer?

Insights Back to resource centre 20 February 2018 Pen-and-paper vs. computerised testing: which method do older adults prefer? Exciting new research shows not only that web-based cognitive assessments are suitable for older adults but, for many, computerised assessments are actually preferable to traditional pen-and-paper tasks. The National Seniors, Flinders Business School and University of Western Australia recently published a study entitled: Better

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